Aug 16, 2016 Atypical fibroxanthoma (AFX) vs mimics (spindle cell melanoma, squamous Skin Metastases & Mimics: Rapid Board Review for Dermatology

Atypical fibroxanthoma is a skin sarcoma (a type of cancer) that tends to grow slowly. (See also Overview of Skin Cancer.) Atypical fibroxanthomas are uncommon but usually occur on the head and neck of older people.

Atypical fibroxanthoma (AFX) is a dermal mesenchymal neoplasm arising in sun-damaged skin, primarily of the head and neck region of older men. Conservative excision cures most. However, varying degrees of subcutaneous involvement can lead to a more aggressive course and rare metastases. Atypical fibroxanthoma (AFX) is a rare skin malignancy generally developed in elderly male patients with actinic damage. Due to its low rate of metastasis, it is considered a benign neoplasm [1,2]. Metastatic AFXs occur in fewer than 6% of patients.

Atypical fibroxanthoma and metastasis to the lung. Atypical fibroxanthoma of the scalp with recurrent and multiple regional within a short period.3,4 The risk of metastasis is increased by tumor depth, Se hela listan på dermatologyadvisor.com Mayo Clinic dermatologic surgeon, Dr. Jerry Brewer discusses Atypical Fibroxanthoma. He tells us about the risk factors, diagnosis and treatment of this rar Cutaneous atypical fibroxanthoma (AFX) occurs in elderly persons as a small nodule or ulcernodule in actinically damaged skin of the head and neck area. The vast majority of AFX behave in a benign manner, and metastasis is rare. Eight examples of metastasizing AFX are reported.

The SPM exhibit aggressive behavior, tendency to invasion and metastatic spread early.

2011-11-10

Abstract. Atypical fibroxanthoma (AFX) is an undifferentiated pleomorphic sarcoma that typically has low-grade malignant potential. Although recurrences do occur, only approximately 25 cases of metastasizing AFX have been reported. Herein a patient with an AFX that metastasized and eventuated in death is described.

A case is presented of postirradiation atypical fibroxanthoma of the skin, metastatic to cervical lymph node, in a young female. Although such skin tumors characteristically have a malignant microscopic appearance, and although they occasionally recur following surgical excision, they have previously been noted for their consistently benign clinical behavior.

Atypical fibroxanthoma (AFX) is a rare spindle cell neoplasm predominantly found on the head and neck of elderly individuals with sun‐damaged skin, with no evidence‐based guidelines for their management. Atypical fibroxanthoma (AFX) is a rare spindle cell neoplasm predominantly found on the head and neck of elderly individuals with sun‐damaged skin, with no evidence‐based guidelines for their management. A case is presented of postirradiation atypical fibroxanthoma of the skin, metastatic to cervical lymph node, in a young female. Although such skin tumors characteristically have a malignant microscopic appearance, and although they occasionally recur following surgical excision, they have previously been noted for their consistently benign clinical behavior. Metastatic Atypical Fibroxanthoma: Case Report of an Uncommon Pathology in the Head and Neck Introduction Atypical fibroxanthoma (AFX) is a rare skin malignancy generally developed in elderly male patients with actinic damage. Due to its low rate of metastasis, it is considered a benign neoplasm [1,2].

Other risk factors include trauma, burns, irradiation, xeroderma pigmentosum, and organ transplantation. 2020-10-14 Atypical fibroxanthoma with regional lymph node metastasis: report of a case and review of the literature. Arch Dermatol. 2010; 146(12):1399-404 (ISSN: 1538-3652) New D; Bahrami S; Malone J; Callen JP. BACKGROUND: Atypical fibroxanthoma (AFX) is a low-grade sarcoma usually occurring on sun-damaged skin of the head and neck in elderly patients. 1986-02-01 BACKGROUND: Atypical fibroxanthoma is a rare cutaneous spindle cell neoplasm typically found on the sun-exposed areas of the head or neck of the elderly. OBJECTIVE: We report a case of localized cutaneous metastases attributed to an atypical fibroxanthoma.
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Usually presents on the sun exposed skin (e.g.

AFX appears clinically as a discrete red or pink nodule or papule …. Atypical fibroxanthoma (AFX) is a dermal Atypical fibroxanthoma (AFX) is an undifferentiated pleomorphic sarcoma that typically has low-grade malignant potential. Although recurrences do occur, only approximately 25 cases of metastasizing AFX have been reported. Herein a patient with an AFX that metastasized and eventuated in death is described.
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2020-09-10

Kargi E, Gungor E, Verdi M, Kuiaçogiu S, Erdogan B, Alli N, et al. Atypical fibroxanthoma and metastasis to the lung.